The James Turrell Skyspace, Light Reign, was unveiled to the public in July of 2003. Since then, it has been the site of numerous meditation sessions, a Quaker silent meeting, a performance art piece, an audio installation by artist Steve Roden, and thousands of individual visits. Combining architecture, sculpture, and atmosphere, the work is not only a spectacular addition to the museum's permanent collection, it has become an important part of the building's architecture.

Turrell's work is meant to be taken in slowly, quietly, and over time. The Skyspace experience varies at different times of the year and different times of day. Visitors are encouraged to stop in again and again to sit back and absorb the effects of the Skyspace over the course of the seasons.

Visitors are also encouraged to swing by the Henry after dark to see the spectrum of intense colors that the exterior of the Skyspace emits when lit by thousands of computer controlled LED lights embedded in its glass panels.